Cadrenal Therapeutics Highlights High Incidence of Thrombotic Complications in Heparin-Induced Thrombocytopenia (HIT) at the J.P. Morgan Healthcare Conference and VLX-1005 as a Potential Therapeutic Solution as the First and Only Selective 12-LOX Inhibitor

MASTER LEGAL DISCLAIMER

Last Updated: Apr 30, 2026

Publisher: Relqo Media LLC (Wyoming, United States)

Subject Company: Cadrenal Therapeutics, Inc. (CVKD)

IMPORTANT SUMMARY, PLEASE READ FIRST

This website and any affiliated digital materials are published by Relqo Media LLC, a Wyoming marketing agency that has been compensated in cash by Penzance LLC to produce and distribute promotional content regarding Cadrenal Therapeutics, Inc. (NASDAQ: CVKD). This communication is a paid advertisement, not a research report, not investment advice, and not an independent publication. Relqo Media is not a broker-dealer, investment adviser, or securities analyst. Investing in small-cap or microcap securities is extremely speculative and may result in the total loss of your investment. We strongly urge all viewers to consult a licensed investment professional and perform their own due diligence.

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Relqo Media LLC is a for-profit marketing agency engaged in paid promotions of public companies. The content we produce is strictly commercial and intended to create temporary public awareness, visibility, and short-term market activity around the featured company. This material is not impartial. All readers should interpret our content as a paid commercial advertisement and not as an editorial, research article, or independent commentary. We create advertisements, not analysis. These Communications are not intended to be factual evaluations of the company's operations or investment merit.

2. COMPENSATION FOR CADRENAL THERAPEUTICS, INC. (CVKD)

Relqo Media LLC ("Relqo Media") has been engaged by Penzance LLC to provide promotional media and digital investor awareness services with respect to Cadrenal Therapeutics, Inc. (NASDAQ: CVKD). The following details outline the nature, scope, and financial terms of this engagement:

• Relqo Media received cash compensation of $25,000 for a 5 day campaign covering April 27th , 2026, through May 1st 2026.
• Relqo Media received cash compensation of $25,000 for a 5 day campaign covering March 9th , 2026, through March 13th 2026.
• Relqo Media received cash compensation of $25,000 for a 4 day campaign covering March 1st , 2026, through March 5th 2026.
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• Relqo Media continued to receive cash compensation on a week to week basis at a rate of $25,000 per week, paid weekly, from July 26, 2025, through September 9, 2025, resulting in aggregate additional compensation of $150,000.
• Relqo Media received additional cash compensation at the same weekly rate of $25,000 per week, paid weekly, covering the period from June 26, 2025, through July 26, 2025, resulting in aggregate compensation of $100,000.
• Relqo Media received cash compensation from Penzance LLC for digital investor awareness and promotional services at a rate of $25,000 per week, paid weekly, beginning January 1, 2025, through July 1, 2025, resulting in aggregate compensation of $650,000 during that period.
• Total Compensation: As of January 19, 2026, Relqo Media has received cumulative cash compensation of $975,000 from Penzance LLC for services rendered in connection with CVKD.
• Future Compensation: This engagement continues on an open ended basis at a rate of $25,000 per week, paid weekly, until terminated by either party. Accordingly, Relqo Media will continue to receive compensation at this rate beyond January 19, 2026, unless and until such agreement is terminated or modified in writing.
• Nature of Services: Relqo Media's services include, but are not limited to, creating, publishing, and distributing digital media, promotional articles, newsletters, websites, investor awareness content, social media campaigns, email/SMS marketing, and other investor-focused communications designed to raise awareness of CVKD among retail and institutional investors.
• Conflict of Interest Statement: Because Relqo Media has been, and will continue to be, compensated directly by Penzance LLC for its services, this relationship represents a material conflict of interest. Relqo Media's communications regarding CVKD, including but not limited to newsletters, articles, press releases, advertisements, websites, emails, SMS alerts, and social media posts, should be understood as paid advertisements that are inherently biased.
• Securities Ownership Disclosure: Penzance LLC and/or its affiliates, officers, directors, or associated individuals may own, acquire, or dispose of securities of Cadrenal Therapeutics, Inc. before, during, or after the campaign period. This means that while Relqo Media is being compensated to promote CVKD, the entities paying for such services may simultaneously engage in securities transactions involving CVKD stock, which could result in gains or losses to those parties independent of Relqo Media's activities.
• Investor Warning: All readers, investors, and market participants should assume that any and all promotional communications disseminated by Relqo Media regarding CVKD are issued for the purpose of increasing investor awareness and may have the effect of increasing trading volume and/or the market price of CVKD's securities. Investors are strongly cautioned to conduct their own independent research, due diligence, and analysis of CVKD, including review of all filings made with the Securities and Exchange Commission (SEC), prior to making any investment decision.

This relationship creates a material conflict of interest. All content distributed by Relqo Media LLC regarding CVKD should be viewed as promotional, financially motivated, and inherently biased.

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